Topical formulation properties including small molecular size, low surface tension, stability, and lipid solubility are crucial for successful topical drug penetration. Increased penetration through the skin and nail can be achieved through a microemulsion drug delivery system. Microemulsions enhance permeation into the skin by: (i) their high solubilization capacity for both lipophilic and hydrophilic compounds increase the loading capacity and dose application; (ii) their large surface area and good skin contact, coupled with their occlusive nature ensures surface contact with …Read More